PhD Studentships In Radiation-Inactivated Virus At University Of Surrey in UK 2022

University of Surrey
PhD Studentships In Radiation-Inactivated Virus At University Of Surrey in UK 2022

Scholarship Description:
Under PhD Studentships In Radiation-Inactivated Virus At University Of Surrey in UK 2022 applications are being invited from eligible candidates. UK and EU Students are eligible to apply for this program. The scholarship allows PhD level programm(s) in the field of Radiation taught at University of Surrey . Interested candidates may apply for the scholarship as per set deadline. The application deadline is 31/03/2022

Subjects offered and Degree Programs:
You can apply for Radiation taught at University of Surrey

Funded by: University of Surrey.

The project aims to investigate the feasibility of using radiation to inactivate viruses for vaccine formulation. The recent Covid-19 pandemic has highlighted the importance of vaccines and the need for faster, economically affordable, and safer vaccine development methods. Vaccines prevent an estimated 3 million deaths/year worldwide but a further 1.5 million lives/year could be saved with better vaccines and wider coverage (Wellcome). Ionizing radiation could provide an alternative option with significant benefits compared to current vaccine formulations. The concept relies on using ionizing radiation to inactivate the virus by damaging its RNA material without destroying the key epitopes or its structural integrity (retaining therefore the full breadth of antigens targets). Simulations have confirmed that this could be achieved with an optimum selection of radiation quality and dose. The inactivated virus would then be used in combination with an adjuvant to stimulate the immune system response. The project will assess the efficiency of different radiation modalities in virus inactivation, establish dose-response curves, develop sample radiation vaccines and compare their efficacy against chemical and other conventional vaccine modalities using a range of biological systems. Cost-effectiveness and ease of manufacturing, including access to radiation facilities and transport, will also be addressed.

The project is a collaboration between the University of Surrey (Radiation and Medical Physics Group and Section of Immunology, School of Biosciences and Medicine) and the National Physical Laboratory.

Sponsor Value

The selected Ph.D. candidates will be provided an annual stipend of £15,609 per annum in addition to the tuition fee at the University of Surrey.

Eligibility Criteria

Candidates must hold a First or 2:1 UK honors degree in a relevant subject area, or a 2:2 alongside a good master’s degree (a distinction is usually required).

This studentship is available to UK or EU candidates.

IELTS requirements: An IELTS Academic of 6.5 or above with 6 in each individual category (or equivalent qualification from other agencies). For more details on English Language requirements see English Language requirements.

Application Procedure

Applications can be made through our Physics Ph.D. course page. Please state the project title and supervisor clearly on all applications.